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ea0011p583 | Neuroendocrinology and behaviour | ECE2006

Spontaneous GH secretion in the fed and fasting states in cranially irradiated adult cancer survivors with normal peak GH responses to two provocative tests: does GH neurosecretory dysfunction exist?

Darzy KH , Murray RD , Gleeson HK , Pezzoli SS , Thorner MO , Shalet SM

A few studies have suggested that radiation-induced growth hormone neurosecretory dysfunction (GHNSD) exists in children irradiated for leukemia (1824 Gy). The presence or absence of GHNSD in adult cancer survivors has not been studied before. Thus, 24-hour spontaneous GH secretion was studied by 20 min sampling both in the fed state (n=16; 6 women) and the last 24 hours of 33-hour fast (n=10; 3 women) in adult cancer survivors, of normal GH status defined ...

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Endocrine Abstracts

Spontaneous GH secretion in the fed and fasting states in cranially irradiated adult cancer survivors with normal peak GH responses to two provocative tests: does GH neurosecretory dysfunction exist?

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